ev_g

Mar Albà 's evolutionary genomics LAB


  • Evolution of new genes
  • The neoantigen landscape of cancer cells
  • all research lines

Vara, C., Montañés, J.C., Albà, M.M. 2024

High polymorphism levels of de novo ORFs in a Yoruba human population

Genome Biology and Evolution 16(7):evae126

Montañés, J.C., Huertas, M., Messeguer, X., Albà, M.M. 2023

Evolutionary trajectories of new duplicated and putative de novo genes

Molecular Biology and Evolution 40(5):msad098

Papadopoulos, C., Albà, M.M. 2023

Newly evolved genes in the human lineage are functional.

Trends in Genetics 39(4):235-236

Montañés, J.C., Huertas, M., Moro, S.G., Blevins, W.R., Carmona, M., Ayté, J., Hidalgo, E., Albà, M.M. 2022

Native RNA sequencing in fission yeast reveals frequent alternative splicing isoforms

Genome Research 32:1215-1227.

Blevins, W.R., Ruiz-Orera, J., Messeguer, X., Blasco-Moreno, B., Villanueva-Cañas, J.L., Espinar, L., Díez, J., Carey, L.B., Albà, M.M. 2021

Uncovering de novo gene birth in yeast using deep transcriptomics

Nature Communications vol. 12:604

Ruiz-Orera, J., Villanueva-Cañas, J.L., Albà, M.M. 2020

Evolution of new proteins from translated sORFs in long non-coding RNAs

Experimental Cell Research vol. 391: 111940 – 111940

Reixachs-Solé, M., Ruiz-Orera, J., Albà, M.M., Eyras, E. 2020

Ribosome profiling at isoform level reveals evolutionary conserved impacts of differential splicing on the proteome

Nature Communications vol. 11: 1768

Ruiz-Orera, J., Albà, M.M. 2019

Conserved regions in long non-coding RNAs contain abundant translation and protein-RNA interaction signatures

Nucleic Acids Research Genomics and Bioinformatics vol. 1: e2

Ruiz-Orera, J., Grau-Verdaguer, P., Villanueva-Cañas, J.L., Messeguer, X., Albà, M.M. 2018

Translation of neutrally evolving peptides provides a basis for de novo gene evolution

Nature Ecology and Evolution vol. 2: 890 – 896

Domazet-Lošo, T., Carvunis, A.R., Albà, M.M., Šestak, M.S., Bakarić, R., Neme, R., Tautz, D. 2017

No evidence for phylostratigraphic bias impacting inferences on patterns of gene emergence and evolution

Molecular Biology and Evolution vol. 34: 843–856

Villanueva-Cañas, J.L., Ruiz-Orera, J., Agea, M.I., Gallo, M., Andreu, D., Albà, M.M. 2017

New genes and functional innovation in mammals

Genome Biology and Evolution vol 9: 1888-1900

Ruiz-Orera, J., Hernández-Rodríguez, J., Chiva, C., Sabidó, E., Kondova, I., Bontrop, R., Marqués-Bonet, T., Albà, M.M. 2015

Origins of de novo genes in human and chimpanzee

Plos Genetics vol 11: e1005721

Radó-Trilla, N., Arató, K., Pegueroles, C., Raya, A., de la Luna, S. *, Albà, M.M. * 2015

Key role of amino acid repeat expansions in the functional diversification of duplicated transcription factors

Molecular Biology and Evolution vol 32: 2263-2272

Ruiz-Orera, J., Messeguer, X., Subirana, J.A., Albà, M.M. 2014

Long non-coding RNAs as a souce of new peptides

eLife vol 3: e03523

Toll-Riera, M., Albà, M.M. 2013

Emergence of novel domains in proteins

BMC Evolutionary Biology vol. 13: 47

Radó-Trilla, N., Albà, M.M. 2012

Dissecting the role of low-complexity regions in the evolution of vertebrate proteins

BMC Evolutionary Biology vol. 12: 155

Toll-Riera, M., Bostick, D., Albà, M.M. *, Plotkin, J.B. * 2012

Structure and age jointly influence rates of protein evolution

PLoS Computational Biology vol. 8: e1002542

Toll-Riera, M., Radó-Trilla, N., Martys, F., Albà, M.M. 2012

Role of Low-Complexity Sequences in the Formation of Novel Protein Coding Sequences

Molecular Biology and Evolution vol. 29, 883-886

Toll-Riera, M., Castelo, R., Bellora, N., Albà, M.M. 2009

Evolution of primate orphan genes

Biochemical Society Transactions vol 37: 778-782

Toll-Riera, M., Bosch, N., Bellora, N., Castelo, R., Armengol, Ll., Estivill, X., Albà, M.M. 2009

Origin of primate orphan genes: a comparative genomics approach

Molecular Biology and Evolution vol 26: 603-612

* co-corresponding

# co-first

Mar Albà 's evolutionary genomics LAB

@ Barcelona Biomedical Research Park (PRBB)